This is a list of notable events, premieres, releases, cancellations, series endings, and other business ventures for Nickelodeon in 2019.
- PAW Patrol, season 6
- SpongeBob SquarePants, season 12
- The Loud House, season 4
- Knight Squad, Season 2
- Hunter Street, Season 3
- The Dude Perfect Show, Season 3
- March 19 - Avatar: The Last Airbender - Team Avatar Tales
- April 30 - The Loud House #6: Loud and Proud
- May 21 - The Legend of Korra: Ruins of the Empire, Part One
- January 8
- Campaign Chaos!
- Lucky: The Adventures of the Unluckiest Leprechaun
- July 16 - The Rise of Kyoshi