Tak: The Great Juju Challenge is the third game in the Tak & the Power of Juju series.
- Jason Marsden - Tak
- Patrick Warburton - Lok
- John Kassir - Jibolba
- Dee Bradley Baker - Dark Juju
- Rob Paulsen - Tlaloc, Dead Juju
- Michael Gough - Announcer Juju
- Jeff Bennett - Two-Headed Juju
- Jennifer Hale - Flora (Tak)
- Tina Illman - Moon Juju
- Candace Bailey - Fauna
- Lara Jill Miller - Dinky Juju
| "Gee, this is harder than I thought."|
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