It starts out at the Krusty Krab where SpongeBob and Patrick are making their favorite noises, while simultaneously annoying Squidward. SpongeBob's is the dolphin laughing and Patrick's is the song of great blue whale. Squidward, who is extremely annoyed at this point, askes them what was happening. They explain that they are doing stuff together out of a book called Simple-ton. They then take a quiz to find out how much they know about each other. SpongeBob does fantastic however, Patrick does terrible. (Just because he is stupid) Not Your Friend Squidward then looks at the book and laughs that Patrick guessed that the shape of SpongeBob was a triangle. Patrick buys two ice cream cones (but only gets Patrick's favorite flavor which is dill pickle swirl with mustard and extra bacon pits) and asks SpongeBob for money. SpongeBob becomes upset, and he tells Patrick that he doesn't know him anymore after tearfully throwing the money on the ground. He then runs off to his house crying. SpongeBob cries so much that he fills up Gary's food bowl. Eventually SpongeBob goes to Sandy for help and she says that they don't have to know everything about each other and they probably just need some time apart. SpongeBob then tries to avoid Patrick, but he sees him go to the gym and many other places with Larry. Patrick is shown with a gift when SpongeBob angrily confronts the two, followed with Larry uncomfortably backing away from them. Patrick then explains that Larry is not his best friend, Larry helped Patrick find a gift for SpongeBob and that he got the gift for SpongeBob, which was a pair of glasses with a fake nose and mustache. SpongeBob and Patrick become friends again until Patrick gets scared by SpongeBob in the glasses and runs away, with SpongeBob quitely sighing "Why me?".
- ? - Sage Guyton, Jeremy Wakefield [title card]
- Seaweed - Steve Belfer [SpongeBob, Patrick making noises]
- ? - Jeremy Wakefield ["Didn't think so."]
- ? ["Huh? Did you hear that?"]
- ? [Simple-Ton magazine]
- ? [best friend quiz]
- ? - Nicolas Carr [Patrick's bellybutton]
- ? - Jeremy Wakefield ["Magic."]
- ? [Patrick taking the quiz]
- ? [Jeopardy-style music]
- ? - Sage Guyton, Jeremy Wakefield ["So, who won your stupid quiz?"]
- ? [ice cream truck]
- ? - Jeremy Wakefield [Patrick asks for five bucks]
- Fates - Gregor F. Narholz ["Here! Take your dirty, rotten money!"]
- ? [SpongeBob crying in bed]
- ? ["Hey there, SpongeBob!"]
- ? - Jeremy Wakefield [at Sandy's]
- Hawaiian Party - Peter Dennis ["I don't need Patrick."]
- ? [SpongeBob hides underground]
- Steel Licks - Jeremy Wakefield ["He doesn't seem to be missing me at all."]
- ? [SpongeBob spying on Patrick]
- Dramatic Impact 6 - Ivor Slaney ["To tell me about your new best friend Larry, I suppose?"]
- ? - Jeremy Wakefield [Larry backs away]
- Pua Paoakalani B - Kapono Beamer, Queen Lili'uokalani [Patrick explains]
- ? - Sage Guyton, Jeremy Wakefield [ending]
- SpongeBob.com released the episode before it premiered on August 9, 2010.
- There was a 3-hour marathon leading up to this episode.
- In this episode, SpongeBob is ambidextrous, but in "I Was a Teenage Gary", he is left-handed. And, in Neptune's Spatula, he has two left hands.
- Though, an explanation for this is that SpongeBob can re-grow his appendages like real sponges.
- When Patrick was asking himself if SpongeBob was left or right handed, he puts his left hand up as he says "right" and his right hand up as he says "left". This is most likely an example of Patrick's stupidity.
- There are 14 jellyfish on the title card.
- In this episode, Patrick is right-handed. However, in "The Camping Episode", Patrick is shown to be writing with his left hand.
- Fancy Living Digest from "Chocolate With Nuts" appears again in this episode.
- Frank from the Palace of Pranks in Pranks a Lot appears again working in the Magic Shop.
- It's revealed that SpongeBob's favorite ice cream is plain vanilla, has an outie bellybutton, and his favorite color is beige. Also, Patrick likes aquamarine, is right-handed, and has an inny bellybutton. His favorite ice cream is a double-pickled swirl with mustard and extra bacon bits.
- The Looney Tunes Show episode "Best Friends" is outwardly similar to this one. In that episode, Bugs and Daffy take a quiz about each other, similar to how SpongeBob and Patrick took a quiz on each other. Also Daffy didn't know anything about Bugs, similar to how Patrick didn't know anything about SpongeBob.
- This episode reveals that Patrick knows nothing about SpongeBob, not even the most simple things about him.
- When SpongeBob gives Patrick the $5, he throws 4 bills and 4 coins on the ground, then cries like crazy. This means that he probably gave Patrick four $1 bills, and four quarter coins.
- The title is a parody of "You Don't Know Jack."
- When Squidward reads down Patrick's answers in Simpleton Magazine, he laughs on the answer "Triangle." However, Simpleton wasn't in SpongeBob's hand when he asked that question. Plus, it wasn't in the quiz.